Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes
Abstract Lysyl hydroxylase 2 (LH2) is a member of LH family that catalyzes the hydroxylation of lysine (Lys) residues on collagen, and this particular isozyme has been implicated in various diseases.While its function as a telopeptidyl LH is generally accepted, several fundamental questions remain unanswered: 1.Does LH2 catalyze the hydroxylation o